This is triggered by internal damage to the vessel wall By Joe D CC 30 via Wikimedia Commons. After adhesion degranulation from both types of granules takes place with the release of various factors. Coagulation And Fibrinolysis Pathway Medical Make It Simple Cross Link Factor III Tissue Factor or TF A condition in which platelet counts are low is known as _____. . This pathway is quicker than the intrinsic pathway. The extrinsic pathway gets turned off after that and the intrinsic pathway takes over but at that point it doesnt matter. Clotting factor I is also known as fibrinogen. The extrinsic and intrinsic coagulation pathways both lead into the final common pathway by independently activating factor X. This system is activated by vascular tissue trauma or surrounding extra-vascular tissue trauma. The extrinsic pathway involves initiation by factor III ie tissue factor and its interaction with factor VII.
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